Duchenne muscular dystrophy (DMD) is an X-linked progressive disease characterized by loss of dystrophin protein that typically results from truncating mutations in the DMD gene.Current exon-skipping therapies have sought to treat deletion mutations that abolish an open reading frame (ORF) by skipping an adjacent exon, in order to restore an ORF th
The Endangered Species Act (ESA) is one of the most powerful and controversial environmental laws in the United States.As a result of its uncompromising position against biodiversity loss, the ESA has become the primary driver of many ecological restoration efforts in Creamers the United States.This article explains why the ESA has become the impet
In mammals the melanocortin 4 receptor (Mc4r) signaling system has been mainly associated with the regulation of appetite and energy homeostasis.In fish of the genus Xiphophorus (platyfish and swordtails) puberty onset is genetically determined by a single locus, which encodes the mc4r.Wild populations of Xiphophorus are polymorphic for early and l
In this research, the impact behavior of nanocomposite sandwich panels with epoxy/fiberglass/nanosilica face sheet were assessed by the finite element method.In the first step, the mechanical properties of the nanoparticle-containing composite should be obtained.A unit cell of fabric was designed in Catia software and placed within the designed pol
Honeybees produce many different products beneficial to humans.One of these of is royal jelly which is the bee product with highest nutritional value but is most difficult to produce.The most time-consuming procedure in royal jelly production involves removing larvae with ideal size from the honeycomb cells and transferring them to queen cups.In or